Airflow Limitation Is Accompanied by Diaphragm Dysfunction

Airflow Limitation and Spirometry

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia accompanied by airflow obstruction.

Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia with airflow obstruction is a rare form of lung injury. All of the reported cases have been diagnosed by surgical lung biopsy. Only three of the reported cases presented with diffuse interstitial lung opacities on HRCT scans. We report three additional cases of this entity. All of the patients were female and presented with mild-to-mo...

Measuring health status in chronic airflow limitation.

A health status instrument for use in clinical trials must be valid (measuring what it is supposed to measure) and responsive (able to detect clinically important change). Approaches to measuring health status in clinical trials include using a battery of instruments, a general instrument which provides a profile of the patient's health, an instrument that generates a health utility, or an inst...

Collapsible airways contributing to airflow limitation.

Dysfunction of the diaphragm.

From the Department of Pulmonary, Critical Care, and Sleep Medicine, Memorial Hospital of Rhode Island, Pawtucket (F.D.M.); the Warren Alpert Medical School of Brown University, Providence, RI (F.D.M.); and the Department of Pathophysiology, University of Athens Medical School, Athens (G.E.T.). Address reprint requests to Dr. McCool at the Department of Pulmonary, Critical Care, and Sleep Medic...